General Information:

Id: 1,989 (click here to show other Interactions for entry)
Diseases: Cardiovascular disease
Diabetes mellitus, type II - [OMIM]
Insulin resistance
Myocardial infarction - [OMIM]
Nephropathy, diabetic
Neuropathy, diabetic
Retinopathy, diabetic
Stroke, ischemic - [OMIM]
Reference: Lardizabal JA and Deedwania PC(2010) The role of renin-angiotensin agents in altering the natural history of type 2 diabetes mellitus Curr Cardiol Rep 12: 464-471 [PMID: 20809236]

Interaction Information:

Comment In patients with IGT, both early and late phases of insulin secretory responses are abnormal, leading to prolonged hyperglycemia after a glucose load. In those with isolated IFG, there is reduction in the early phase of insulin secretory response, which causes fasting hyperglycemia; however, the late phase response is preserved, which allows the normalization of blood sugar levels after a glucose load.
Formal Description
Interaction-ID: 15638

affects_activity of

in pancreas; in early and late phase