General Information:

Id: 1,441 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Hemochromatosis, type 1 - [OMIM]
Reference: Cahill CM et al.(2009) Amyloid precursor protein and alpha synuclein translation, implications for iron and inflammation in neurodegenerative diseases Biochim. Biophys. Acta 1790: 615-628 [PMID: 19166904]

Interaction Information:

Comment Individuals homozygous for the E4 allele of apolipoprotein E (ApoE) are at increased risk for developing Alzheimer's disease.
Formal Description
Interaction-ID: 10320

gene/protein mutant

APOE (isoform E4)

increases_activity of