General Information:

Id: 1,311 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Mus musculus
male
ob/ob mouse
article
Reference: Ozcan U et al.(2006) Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes Science 5790: 1137-1140 [PMID: 16931765]

Interaction Information:

Comment The authors found that administration of both PBA and TUDCA significantly suppressed hepatic glucose production (HGP) at baseline and during the clamp studies.
Formal Description
Interaction-ID: 8988

drug/chemical compound

Sodium phenylbutyrate

decreases_activity of

process

gluconeogenesis

in liver