General Information:

Id: 1,154 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Amyotrophic lateral sclerosis
Parkinson disease
Mus musculus
APP TgCRND8 (AD animal model), (Thy1)-[A30P]a-SYN (PD/DLB animal model), Tg(SOD1-G93A) ALS model
Reference: Letiembre M et al.(2009) Screening of innate immune receptors in neurodegenerative diseases: a similar pattern Neurobiol. Aging 30: 759-768 [PMID: 17905482]

Interaction Information:

Comment The toll-like receptors (TLR's), in this attempt TLR2 and the LPS receptor CD14 are known to trigger a massive inflammatory host response.
Formal Description
Interaction-ID: 8246



affects_activity of

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