General Information:

Id: 1,092 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Obesity - [OMIM]
Reference: de Luca C and Olefsky JM(2008) Inflammation and insulin resistance FEBS Lett. 582: 97-105 [PMID: 18053812]

Interaction Information:

Comment Il-10 is an anti-inflammatory cytokine produced by macrophages and lymphocytes. Il-10 exerts its anti-inflammatory activity by inhibiting Tnf-induced NF-kappa-B activation by reducing IKK activity.
Formal Description
Interaction-ID: 7274


NF-kappaB complex

increases_activity of