General Information:

Id: 6,618 (click here to show other Interactions for entry)
Diseases: Q fever
pathogen-host system
Coxiella burnetii/mammalia
primary mouse macrophages, coinfected with C. burnetii strain RSA 493 phase II and L. pneumophila
article
Reference: Cunha LD et al.(2015) Inhibition of inflammasome activation by Coxiella burnetii type IV secretion system effector IcaA Nat Commun 6: 10205 [PMID: 26687278]

Interaction Information:

Comment The authors identified CBU_1823 as a C. burnetii effector protein that is secreted by the Dot/Icm type IV secretion system. CBU_1823 has been renamed to IcaA (inhibitor of caspase activation).
Formal Description
Interaction-ID: 63073

process

T4BSS

increases_transport of

gene/protein

CBU_1823

into murine macrophages