General Information:

Id: 6,618 (click here to show other Interactions for entry)
Diseases: Q fever
pathogen-host system
Coxiella burnetii/mammalia
primary mouse macrophages, coinfected with C. burnetii strain RSA 493 phase II and L. pneumophila
article
Reference: Cunha LD et al.(2015) Inhibition of inflammasome activation by Coxiella burnetii type IV secretion system effector IcaA Nat Commun 6: 10205 [PMID: 26687278]

Interaction Information:

Comment Caspase-1 is not activated in murine bone marrow-derived macrophages (BMDMs) infected with C. burnetii.
Formal Description
Interaction-ID: 63071

process

Coxiella burnetii infection

NOT increases_activity of

gene/protein

CASP1

in macrophages
Drugbank entries Show/Hide entries for CASP1