General Information:

Id: 6,616 (click here to show other Interactions for entry)
Diseases: Pseudomonas aeruginosa diseases
pathogen-host system
Pseudomonas aeruginosa/mammalia
human mucoid bronchial epithelial cell line, H292 treated with pyocyanin
article
Reference: Rada B et al.(2011) Reactive oxygen species mediate inflammatory cytokine release and EGFR-dependent mucin secretion in airway epithelial cells exposed to Pseudomonas pyocyanin Mucosal Immunol 4: 158-171 [PMID: 20962773]

Interaction Information:

Comment IL-1-beta, IL-6, TGF-alpha and TNF-alpha appear to signal upstream of EGFR to induce release of MUC5AC.
Formal Description
Interaction-ID: 63024

gene/protein

TNF

increases_quantity of

gene/protein

MUC5AC

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