General Information:

Id: 6,616 (click here to show other Interactions for entry)
Diseases: Pseudomonas aeruginosa diseases
pathogen-host system
Pseudomonas aeruginosa/mammalia
human mucoid bronchial epithelial cell line, H292 treated with pyocyanin
article
Reference: Rada B et al.(2011) Reactive oxygen species mediate inflammatory cytokine release and EGFR-dependent mucin secretion in airway epithelial cells exposed to Pseudomonas pyocyanin Mucosal Immunol 4: 158-171 [PMID: 20962773]

Interaction Information:

Comment Five cytokines (IL-1-alpha, IL-1-beta, IL-6, IL-8, TNF-alpha) and two EGFR ligands (TGF-alpha, HB-EGF) were strongly up-regulated by pyocyaninin TBECs (tracheobronchiolar epithelial cells).
Formal Description
Interaction-ID: 63014

drug/chemical compound

Pyocyanine

increases_expression of

gene/protein

TNF

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