human lung fibroblast cell line (IMR-90), incubated with Pseudomonas aeruginosa produced elastase (PE) with
Azghani AO et al.(2014) Mechanism of fibroblast inflammatory responses to Pseudomonas aeruginosa elastase Microbiology (Reading 160: 547-555
P. aeruginosa produced elastase (PE) treatment increases the activation of NF-kB in fibroblasts. PE-treated monolayers showed a significant increase in NF-kB nuclear translocation that was detectable by 10 min
and was sustained for an hour.
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