General Information:

Id: 6,554 (click here to show other Interactions for entry)
Diseases: Pseudomonas aeruginosa diseases
pathogen-host system
Pseudomonas aeruginosa/mammalia
human lung fibroblast cell line (IMR-90), incubated with Pseudomonas aeruginosa produced elastase (PE) with
article
Reference: Azghani AO et al.(2014) Mechanism of fibroblast inflammatory responses to Pseudomonas aeruginosa elastase Microbiology (Reading 160: 547-555 [PMID: 24385476]

Interaction Information:

Comment P. aeruginosa produced elastase (PE) increases the level of phosphorylated ERK1/2 kinases in human lung fibroblasts. PE activates ERK1/2 in a concentration- and timedependent fashion.
Formal Description
Interaction-ID: 62291

gene/protein

lasB

increases_activity of

gene/protein

MAPK1

Drugbank entries Show/Hide entries for lasB or MAPK1