General Information:

Id: 6,543 (click here to show other Interactions for entry)
Diseases: Pseudomonas aeruginosa diseases
pathogen-host system
Pseudomonas aeruginosa/mammalia
P. aeruginosa PAO1 and different PA14 strains
article
Reference: Moura-Alves P et al.(2014) AhR sensing of bacterial pigments regulates antibacterial defence Nature 512: 387-392 [PMID: 25119038]

Interaction Information:

Comment Phenazines are major AhR activators in P. aeruginosa. Sensing of the bacterial pigments pyocyanin (Pyo) and 1-hydroxyphenazine (1-HP) of P. aeruginosa by AhR caused their direct degradation.
Formal Description
Interaction-ID: 62224

gene/protein

AHR

decreases_quantity of

drug/chemical compound

1-hydroxyphenazine

as shown in supernatants of A549 Scramble and AhR-KD cells, 48 h after stimulation
Drugbank entries Show/Hide entries for AHR