General Information:

Id: 5,267 (click here to show other Interactions for entry)
Diseases: Pseudomonas aeruginosa diseases
pathogen-host system
Pseudomonas aeruginosa/mammalia
Rat pulmonary microvascular endothelial cells (PMVECs), infected with P. aeruginosa strain 388
article
Reference: Balczon R et al.(2013) Pseudomonas aeruginosa exotoxin Y-mediated tau hyperphosphorylation impairs microtubule assembly in pulmonary microvascular endothelial cells PLoS ONE 8 [PMID: 24023939]

Interaction Information:

Comment ExoY activity causes a decrease in microtubules, as shown by infection of PMVECs with P.aeruginosa expressing either non-functional K81M mutant ExoY or wild type ExoY.
Formal Description
Interaction-ID: 51349

gene/protein

exoY

decreases_quantity of

cellular component

microtubule cytoskeleton