General Information:

Id: 4,511 (click here to show other Interactions for entry)
Diseases: Pseudomonas aeruginosa diseases
pathogen-host system
Pseudomonas aeruginosa/mammalia
human corneal epithelial cells (hTCEpi), infected with P. aeruginosa strain PAO1
article
Reference: Heimer SR et al.(2013) Pseudomonas aeruginosa Utilizes the Type III Secreted Toxin ExoS to Avoid Acidified Compartments within Epithelial Cells PLoS ONE 8 [PMID: 24058462]

Interaction Information:

Comment High exoS transcriptional output coincided with low occupation of acidified vacuoles, and vice versa, for both popB mutants and wild-type bacteria. Translocon (popB) mutants and wild-type bacteria, which can both replicate intracellularly (due to their capacity to secrete ExoS), showed little or no colocalization with acidified vacuoles, compared to the exsA mutant (unable to express ExoS).
Formal Description
Interaction-ID: 45115

gene/protein

exoS

decreases_activity of