General Information:

Id: 4,475 (click here to show other Interactions for entry)
Diseases: Pseudomonas aeruginosa diseases
pathogen-host system
Pseudomonas aeruginosa/mammalia
Human telomerase-immortalized corneal epithelial cells (hTCEpi), infected with P. aeruginosa strain PAO1
Reference: Angus AA et al.(2010) The ADP-ribosylation domain of Pseudomonas aeruginosa ExoS is required for membrane bleb niche formation and bacterial survival within epithelial cells Infect. Immun. 78: 4500-4510 [PMID: 20732998]

Interaction Information:

Comment Bleb niches display apoptotic markers. ExoS-mediated bleb niches were found to be strongly labeled with the apoptotic marker annexin V-EGFP, which recognizes externalized phosphatidylserine, an early apoptotic cell marker.
Formal Description
Interaction-ID: 45049


membrane bleb niche formation

increases_activity of

in human corneal epithelial cells (hTCEpi)