General Information:

Id: 4,410 (click here to show other Interactions for entry)
Diseases: Q fever
pathogen-host system
Coxiella burnetii / mammalia
human monocytic TH1 cells, infected with C. burnetii (RSA439) NMII
article
Reference: Macdonald LJ et al.Coxiella burnetii exploits host cAMP-dependent protein kinase signalling to promote macrophage survival [PMID: 24028560]

Interaction Information:

Comment The results indicate PKA inhibition impairs C. burnetii's capacity to prevent PARP cleavage and protect its host cell from apoptotic death.
Formal Description
Interaction-ID: 44826

process

Coxiella burnetii infection

decreases_processing of

gene/protein

PARP1

Drugbank entries Show/Hide entries for PARP1