General Information:

Id: 4,337 (click here to show other Interactions for entry)
Diseases: Pseudomonas aeruginosa diseases
pathogen-host system
Pseudomonas aeruginosa/mammalia
sputum of CF (cystic fribrosis) patients
article
Reference: Konings AF et al.(2013) Pseudomonas aeruginosa uses multiple pathways to acquire iron during chronic infection in cystic fibrosis lungs Infect. Immun. 81: 2697-2704 [PMID: 23690396]

Interaction Information:

Comment The authors analysed the sputum of CF (cystic fibrosis) patients by RT-qPCR. Ferrous ions can be internalized into P. aeruginosa through the inner membrane permease FeoB. In sputum, feoB transcripts were detected in all 53 samples examined.
Formal Description
Interaction-ID: 44397

process

P. aeruginosa infection, chronic

increases_expression of

gene/protein

feoB

in sputum of all CF patients