General Information:

Id: 4,265 (click here to show other Interactions for entry)
Diseases: Pseudomonas aeruginosa diseases
pathogen-host system
Pseudomonas aeruginosa/mammalia
mouse embryonic fibroblasts, MEFs, challenged withN-(3-oxododecanoyl)-HSL (C12)
article
Reference: Valentine CD et al.(2013) X-Box Binding Protein 1 (XBP1s) Is a Critical Determinant of Pseudomonas aeruginosa Homoserine Lactone-Mediated Apoptosis PLoS Pathog. 9 [PMID: 23990788]

Interaction Information:

Comment According to earlier studies increased phospho-eIF2-alpha (peIF2-alpha) and phospho-p38 MAPK (p-p38 MAPK could also be detected in wt MEFs after C12 (N-(3-oxododecanoyl)-HSL) exposure for 45 minutes.
Formal Description
Interaction-ID: 43590

drug/chemical compound

N-(3-Oxododecanoyl)-HSL

increases_phosphorylation of

gene/protein

p38 MAPK

in mouse embryonic fibroblasts