General Information:

Id: 3,949 (click here to show other Interactions for entry)
Diseases: Pseudomonas aeruginosa diseases
pathogen-host system
intrabacterial interactions and heterologous bacterial interactions Pseudomonas aeruginosa/Pseudomonas putida
P. aeruginosa strain PAO1
article
Reference: Russell AB et al.(2013) Diverse type VI secretion phospholipases are functionally plastic antibacterial effectors Nature 496: 508-512 [PMID: 23552891]

Interaction Information:

Comment Specific inactivation of the H2-T6SS in a donor strain abrogated Tle5 (PA3487, type VI lipase effector 5)-dependent toxicity, indicating that this system is responsible for Tle5 delivery. The results showed that both Tle5 and the H2-T6SS significantly contribute to the fitness of P. aeruginosa in interspecies competition (P. aeruginosa/P. putida) under T6S-conducive conditions.
Formal Description
Interaction-ID: 40090

process

T6SS-HSI-2

increases_transport of

gene/protein

tle5

Comment Specific inactivation of the H2-T6SS in a donor strain abrogated Tle5 (PA3487, type VI lipase effector 5)-dependent toxicity, indicating that this system is responsible for Tle5 delivery. The results showed that both Tle5 and the H2-T6SS significantly contribute to the fitness of P. aeruginosa in interspecies competition (P. aeruginosa/P. putida) under T6S-conducive conditions.
Formal Description
Interaction-ID: 40096

process

T6SS-HSI-2

increases_activity of

process

T6SS dueling

Comment Specific inactivation of the H2-T6SS in a donor strain abrogated Tle5 (PA3487, type VI lipase effector 5)-dependent toxicity, indicating that this system is responsible for Tle5 delivery. The results showed that both Tle5 and the H2-T6SS significantly contribute to the fitness of P. aeruginosa in interspecies competition (P. aeruginosa/P. putida) under T6S-conducive conditions.
Formal Description
Interaction-ID: 45380

process

T6SS-HSI-2

increases_activity of

process

killing of other bacteria