General Information:

Id: 3,902 (click here to show other Interactions for entry)
Diseases: Pseudomonas aeruginosa diseases
pathogen-host system
P. aeruginosa strain PA14 grown with GlcNAc as the primary carbon and energy source
article
Reference: Korgaonkar AK and Whiteley M(2011) Pseudomonas aeruginosa enhances production of an antimicrobial in response to N-acetylglucosamine and peptidoglycan J. Bacteriol. 193: 909-917 [PMID: 21169497]

Interaction Information:

Comment In addition to genes putatively involved in N-acetylglucosamine (GlcNAc) catabolism, genes encoding factors important for killing eukaryotic and prokaryotic cells were induced during growth with GlcNAc as the primary carbon and energy source. These genes are involved in phenazine biosynthesis, as well as genes encoding the extracellular proteases LasA and LasB.
Formal Description
Interaction-ID: 39599

drug/chemical compound

N-Acetyl-D-glucosamine

increases_expression of

gene/protein

lasB

in P. aeruginosa, grown with GlcNAc as the primary carbon and energy source
Drugbank entries Show/Hide entries for N-Acetyl-D-glucosamine or lasB