General Information:

Id: 3,900 (click here to show other Interactions for entry)
Diseases: Pseudomonas aeruginosa diseases
pathogen-host system
Pseudomonas aeruginosa/heterologous host
P. aeruginosa strain PA14, treated with peptidoglycan
article
Reference: Korgaonkar A et al.(2013) Community surveillance enhances Pseudomonas aeruginosa virulence during polymicrobial infection Proc. Natl. Acad. Sci. U.S.A. 110: 1059-1064 [PMID: 23277552]

Interaction Information:

Comment The addition of GlcNAc (N-acetylglucosamine) and the GlcNAc-containing polymer peptidoglycan (exogenous peptidoglycan, originating from commensal Gram-positive bacteria) to P. aeruginosa results in enhanced production of the virulence factors pyocyanin, elastase and Pseudomonas quinolone signal, PQS (2-heptyl-3-hydroxy-4-quinolone).
Formal Description
Interaction-ID: 39553

cellular component

peptidoglycan, exogenous

increases_quantity of

gene/protein

lasB

in P. aeruginosa
Drugbank entries Show/Hide entries for lasB