General Information:

Id: 3,862 (click here to show other Interactions for entry)
Diseases: Pseudomonas aeruginosa diseases
pathogen-host system
Pseudomonas aeruginosa/mammalia
HeLa cells, infected with P. aeruginisa strain (GESPA 1999 collection)
article
Reference: Gendrin C et al.(2012) Structural basis of cytotoxicity mediated by the type III secretion toxin ExoU from Pseudomonas aeruginosa PLoS Pathog. 8 [PMID: 22496657]

Interaction Information:

Comment In protein-lipid overlay assays it has been demonstrated that ExoU strongly interacts with PI(4,5)P2 (phosphatidylinositol (4,5) di-phosphate), a negatively-charged polyvalent phospholipid that is abundant in the cytosolic leaflet of the PM (plasma membrane).
Formal Description
Interaction-ID: 38813

gene/protein

exoU

interacts (colocalizes) with