General Information:

Id: 3,862 (click here to show other Interactions for entry)
Diseases: Pseudomonas aeruginosa diseases
pathogen-host system
Pseudomonas aeruginosa/mammalia
HeLa cells, infected with P. aeruginisa strain (GESPA 1999 collection)
article
Reference: Gendrin C et al.(2012) Structural basis of cytotoxicity mediated by the type III secretion toxin ExoU from Pseudomonas aeruginosa PLoS Pathog. 8 [PMID: 22496657]

Interaction Information:

Comment To analyse the multi-faceted behavior of ExoU, the authors solved its crystal structure, which was achieved in the presence of its chaperone, SpcU. ExoU forms a 1:1 complex with SpcU, and folds into three distinct domains, which fulfill catalytic, bridging, and membrane-binding functions.
Formal Description
Interaction-ID: 38811

gene/protein

spcU

interacts (colocalizes) with

gene/protein

exoU

as shown in a crystal structure