General Information:

Id: 3,810 (click here to show other Interactions for entry)
Diseases: Q fever
pathogen-host system
Coxiella burnetii/mammalia
HeLa cells, siRNA treated, infected with C. burnetii NMII, producing BlaM-77 fusion protein
article
Reference: McDonough JA et al.(2013) Host pathways important for Coxiella burnetii infection revealed by genome-wide RNA interference screening MBio 4 [PMID: 23362322]

Interaction Information:

Comment Depletion of VPS35 levels by gene silencing resulted in a defect in BlaM-77 translocation, showing that the retromer pathway is important for delivery of C. burnetii effectors.
Formal Description
Interaction-ID: 38078

complex/PPI

Retromer complex

increases_activity of

process

T4BSS