General Information:

Id: 3,805 (click here to show other Interactions for entry)
Diseases: Q fever
pathogen-host system
Coxiella burnetii/mammalia
HeLa cells, infected with C. burnetii NMII, producing BlaM-effector fusion proteins BlaM alone, BlaM-77, BlaM-1823, BlaM-1524
Reference: Newton HJ et al.(2013) Effector Protein Translocation by the Coxiella burnetii Dot/Icm Type IV Secretion System Requires Endocytic Maturation of the Pathogen-Occupied Vacuole PLoS ONE 8 [PMID: 23349930]

Interaction Information:

Comment The results show that maturation of the Coxiella containing vacuole, CCV to a late-endocytic compartment through the activities of Rab5 and Rab7 stimulate delivery of effectors by the Dot/Icm system.
Formal Description
Interaction-ID: 37909

increases_activity of



in C. burnetii infected HeLa cells