General Information:

Id: 3,770 (click here to show other Interactions for entry)
Diseases: Q fever
pathogen-host system
Coxiella burnetii/mammalia
bone marrow-derived macrophages (BMDMs), infected with virulent/avirulent (phase I/phase II) C. burnetii or virulent/avirulent LPS (vLPS/avLPS)
article
Reference: Barry AO et al.(2012) Impaired Stimulation of p38alpha-MAPK/Vps41-HOPS by LPS from Pathogenic Coxiella burnetii Prevents Trafficking to Microbicidal Phagolysosomes Cell Host Microbe 12: 751-763 [PMID: 23245320]

Interaction Information:

Comment Inhibition of p38alpha-MAPK blocked the phosphorylation of Vps41 in BMDMs challenged with avLPS (avirulent.
Formal Description
Interaction-ID: 36826

gene/protein

p38 MAPK

increases_activity of

gene/protein

VPS41

in BMDMs; infected with avirulent LPS