General Information:

Id: 3,770 (click here to show other Interactions for entry)
Diseases: Q fever
pathogen-host system
Coxiella burnetii/mammalia
bone marrow-derived macrophages (BMDMs), infected with virulent/avirulent (phase I/phase II) C. burnetii or virulent/avirulent LPS (vLPS/avLPS)
Reference: Barry AO et al.(2012) Impaired Stimulation of p38alpha-MAPK/Vps41-HOPS by LPS from Pathogenic Coxiella burnetii Prevents Trafficking to Microbicidal Phagolysosomes Cell Host Microbe 12: 751-763 [PMID: 23245320]

Interaction Information:

Comment The p38alpha-MAPK upstream activator MKK3/6 has not been induced in BMDMs stimulated with C. burnetii vLPS (virulent), but in BMDMs stimulated with C. burnetii avLPS (avirulent)
Formal Description
Interaction-ID: 36799



increases_activity of


p38 MAPK