General Information:

Id: 3,724 (click here to show other Interactions for entry)
Diseases: Q fever
pathogen-host system
Coxiella burnetii/mammalia
CHO cells, infected with Dot/Icm-sufficient LP01 strain of L. pneumophila, expressing Cya fusions to the indicated C. burnetii proteins or HeLa cells expressing FLAG-tagged C. burnetii proteins
article
Reference: Carey KL et al.(2011) The Coxiella burnetii Dot/Icm system delivers a unique repertoire of type IV effectors into host cells and is required for intracellular replication PLoS Pathog. 7 [PMID: 21637816]

Interaction Information:

Comment The authors identified 18 different C. burnetii proteins that are effectors delivered into host cells by the L. pneumophila Dot/Icm apparatus.
Formal Description
Interaction-ID: 36221

process

T4BSS

increases_transport of

gene/protein

CBU_1825

into the host cell mitochondria of HeLa cells; shown in a CyaA translocation assay of C. burnetii proteins by the L. pneumophila Dot/Icm apparatus