General Information:

Id: 3,720 (click here to show other Interactions for entry)
Diseases: Q fever
pathogen-host system
Coxiella burnetii/mammalia
article/cited
Reference: Klingenbeck L et al.The Coxiella burnetii type IV secretion system substrate CaeB inhibits intrinsic apoptosis at the mitochondrial level [PMID: 23126667]

Interaction Information:

Comment It has been shown that the effector proteins CaeA (CBU1524) and CaeB (CBU1532) are transcribed during infection and that they are translocated in a T4SS-dependent manner. CBU1524 (C. burnetii anti-apoptotic effector A, CaeA) displayed nuclear localization when ectopically expressed. (cited information)
Formal Description
Interaction-ID: 36129

process

T4BSS

increases_transport of

gene/protein

caeA

into host cell nucleus