General Information:

Id: 3,711 (click here to show other Interactions for entry)
Diseases: Q fever
pathogen-host system
Coxiella burnetii/mammalia
HEK293 cells, CHO cells, HeLa cells infected with C. burnetii strain NMII
article
Reference: Klingenbeck L et al.The Coxiella burnetii type IV secretion system substrate CaeB inhibits intrinsic apoptosis at the mitochondrial level [PMID: 23126667]

Interaction Information:

Comment Thereo were no obvious differences in the protein levels of the pro-apoptotic, BH3-only proteins Bim and Puma, while there was an upregulation of Bid in GFP-CaeB expressing HEK293 cells. There were no differences in the protein levels of Bak and Bax.
Formal Description
Interaction-ID: 36151

gene/protein

BCL2L11

increases_activity of

process

host cell apoptosis