General Information:

Id: 3,707 (click here to show other Interactions for entry)
Diseases: Q fever
pathogen-host system
Coxiella burnetii/mammalia
review
Reference: Hussain SK and Voth DE(2012) Coxiella subversion of intracellular host signaling Adv. Exp. Med. Biol. 984: 131-140 [PMID: 22711630]

Interaction Information:

Comment At the transcriptional level C. burnetii infected THP-1 cells show decreased expression of pro-apoptotic bax, bim, bik, casp2, and casp6, contributing to an overall anti-apoptotic state.
Formal Description
Interaction-ID: 35993

gene/protein

BAX

increases_activity of

process

host cell apoptosis