General Information:

Id: 3,707 (click here to show other Interactions for entry)
Diseases: Q fever
pathogen-host system
Coxiella burnetii/mammalia
review
Reference: Hussain SK and Voth DE(2012) Coxiella subversion of intracellular host signaling Adv. Exp. Med. Biol. 984: 131-140 [PMID: 22711630]

Interaction Information:

Comment At the transcriptional level C. burnetii infected THP-1 cells show increased expression of cIAP2 (BIRC3), a1/bfl-1, and bag1, which promote survival. The protein level of cIAP2 and A1/Bfl-1 also dramatically increases during infection.
Formal Description
Interaction-ID: 35973

gene/protein

BIRC3

decreases_activity of

process

host cell apoptosis