General Information:

Id: 3,688 (click here to show other Interactions for entry)
Diseases: Q fever
pathogen-host system
Coxiella burnetii/mammalia
Reference: Capo C and Mege JL(2012) Role of innate and adaptive immunity in the control of q Fever Adv. Exp. Med. Biol. 984: 273-286 [PMID: 22711637]

Interaction Information:

Comment IFN-gamma up-regulates TNF production and induces the expression of membrane TNF. Neutralizing TNF with specific antibodies prevents macrophage apoptosis and the eradication of C. burnetii.
Formal Description
Interaction-ID: 35429



increases_activity of


host cell apoptosis

of C. burnetii-infected macrophages
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