General Information:

Id: 3,653 (click here to show other Interactions for entry)
Diseases: Q fever
pathogen-host system
Coxiella burnetii/mammalia
review
Reference: Amara AB et al.(2012) Immune Response and Coxiella burnetii Invasion Adv. Exp. Med. Biol. 984: 287-298 [PMID: 22711638]

Interaction Information:

Comment In circulating monocytes, C. burnetii stimulates an M1-type activation that controls bacterial replication. The M1-type activation is associated with the release of: TNF, IL-6, IL-12, CD80, CCR7, IFN-gamma and NO production.
Formal Description
Interaction-ID: 34773

process

M1 polarization

increases_quantity of

gene/protein

TNF

in monocytes; in response to C. burnetii infection
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