General Information:

Id: 3,568 (click here to show other Interactions for entry)
Diseases: Q fever
pathogen-host system
Coxiella burnetii/mammalia
THP-1 cells, or HeLa cells, infected with avirulent C. burnetii phase II
article
Reference: Hussain SK et al.(2010) Host Kinase Activity is Required for Coxiella burnetii Parasitophorous Vacuole Formation Front Microbiol 1: 137 [PMID: 21772829]

Interaction Information:

Comment The results show that numerous signaling proteins, including PRL1, PKC, PKA, and MLCK are involved in PV maturation events and do not have bactericidal effects on C. burnetii. The removing of the corresponding inhibitors from the infected cells resulted in PV maturation, with CD63-positive vacuoles present at 48 h post-washout.
Formal Description
Interaction-ID: 33351

gene/protein

MYLK

increases_activity of