General Information:

Id: 3,521 (click here to show other Interactions for entry)
Diseases: Q fever
pathogen-host system
Coxiella burnetii/mammalia
Reference: McDonough JA et al.(2012) Coxiella burnetii Secretion Systems Adv. Exp. Med. Biol. 984: 171-197 [PMID: 22711632]

Interaction Information:

Comment The Dot/Icm type IV secretion system has been analysed in C. burnetii in homology to L. pneumophila. Examination of the relative transcript levels concerning the three operons icmW-CBU1651-icmX, icmV-dotA-CBU1647 and icmT-icmSicmD-icmC-icmB-CBU1646 showed an increased transcription of these genes during the initial 16 h of C. burnetii infection of a eukaryotic host cell, and a subsequent drop in transcript levels by 24 h post-infection.
Formal Description
Interaction-ID: 32748


Coxiella burnetii infection

increases_expression of



during the initial 16 h of infection