General Information:

Id: 3,498
Diseases: Q fever
pathogen-host system
Coxiella burnetii/mammalia
ectopically expressed plasmid T4SS substrates in HeLa cells as fusions to green fluorescent protein (GFP)
article
Reference: Voth DE et al.(2011) The Coxiella burnetii cryptic plasmid is enriched in genes encoding type IV secretion system substrates J. Bacteriol. 193: 1493-1503 [PMID: 21216993]

Interaction Information:

Comment It has been demonstrated that GFP-CpeB trafficked to vesicular structures, including the PV membrane and to autophagosomes, as evidenced by colocalization with LC3B.
Formal Description
Interaction-ID: 32477

process

T4BSS

increases_transport of

gene/protein

cpeB

to the PV membrane and to autophagosomes; in HeLa cells as fusion to GFP
Comment It has been demonstrated that CpeD localized to filamentous structures and partially to the endoplasmic reticulum (ER), as indicated by colocalization with calnexin.
Formal Description
Interaction-ID: 32480

process

T4BSS

increases_transport of

gene/protein

cpeD

to filamentous structures and partially to the endoplasmic reticulum; in HeLa cells as fusion to GFP
Comment It has been demonstrated that GFP-CpeA and GFP-CpeC localized to small cytoplasmic puncta.
Formal Description
Interaction-ID: 36285

process

T4BSS

increases_transport of

gene/protein

cpeA

to small cytoplasmic puncta; in HeLa cells as fusion to GFP
Comment It has been demonstrated that GFP-CpeA and GFP-CpeC localized to small cytoplasmic puncta.
Formal Description
Interaction-ID: 36288

process

T4BSS

increases_transport of

gene/protein

cpeC

to small cytoplasmic puncta; in HeLa cells as fusion to GFP