General Information:

Id: 3,484 (click here to show other Interactions for entry)
Diseases: Q fever
pathogen-host system
Coxiella burnetii/mammalia
THP-1 macrophages, infected with C. burnetii Nine Mile phase II (NMII)
Reference: Beare PA et al.(2012) Two Systems for Targeted Gene Deletion in Coxiella burnetii Appl. Environ. Microbiol. 78: 4580-4589 [PMID: 22522687]

Interaction Information:

Comment The lack of intracellular replication by delta-dotA and delta-dotB mutants correlated with failed production of the large and spacious replication vacuole typical of C. burnetii infection.
Formal Description
Interaction-ID: 32414



increases_activity of

shown in Vero cells; analysed in delta-dotA and delta-dotB mutants