General Information:

Id: 3,484 (click here to show other Interactions for entry)
Diseases: Q fever
pathogen-host system
Coxiella burnetii/mammalia
THP-1 macrophages, infected with C. burnetii Nine Mile phase II (NMII)
article
Reference: Beare PA et al.(2012) Two Systems for Targeted Gene Deletion in Coxiella burnetii Appl. Environ. Microbiol. 78: 4580-4589 [PMID: 22522687]

Interaction Information:

Comment The C. burnetii proteins dotA and dotB, are probable structural components of the type IVB secretion system (T4BSS). Delta-dotA and delta-dotB mutants failed to secrete T4BSS substrates and to productively infect host cells.
Formal Description
Interaction-ID: 32372

gene/protein

dotaA

increases_activity of

process

T4BSS

analysed in delta-dotA and delta-dotB mutants