General Information:

Id: 3,419 (click here to show other Interactions for entry)
Diseases: Pseudomonas aeruginosa diseases
pathogen-host system
Pseudomonas aeruginosa/mammalia
MDCK or Caco-2 cells, infected with P. aeruginosa strain PAO1
article
Reference: Okuda J et al.(2010) Translocation of Pseudomonas aeruginosa from the intestinal tract is mediated by the binding of ExoS to an Na,K-ATPase regulator, FXYD3 Infect. Immun. 78: 4511-4522 [PMID: 20805335]

Interaction Information:

Comment In a GST pulldown assay it was shown that ExoS binds to FXYD3, a regulator of Na,K-ATPase. A further experiment showed that ExoS was detected only in FXYD3 complexes precipitated from PAO1-infected Caco-2 cell lysates.
Formal Description
Interaction-ID: 31769

gene/protein

exoS

interacts (colocalizes) with

gene/protein

FXYD3

in a GST pulldown assay and Caco-2 cell lysates