General Information:

Id: 3,415 (click here to show other Interactions for entry)
Diseases: Pseudomonas aeruginosa diseases
pathogen-host system
Pseudomonas aeruginosa/mammalia
BTO:0000195 CACO-2 cell monolayers, infected with P. aeruginosa strain PAO1
article
Reference: Okuda J et al.(2011) Degradation of interleukin 8 by the serine protease MucD of Pseudomonas aeruginosa J. Infect. Chemother. 17: 782-792 [PMID: 21626303]

Interaction Information:

Comment The experiments suggest that the serine protease MucD, which is regulated by ExoS, directly or indirectly degrades IL-8 so that IL-8-dependent neutrophil infiltration and successive bacterial killing are attenuated.
Formal Description
Interaction-ID: 31705

gene/protein

exoS

affects_activity of

gene/protein

mucD