General Information:

Id: 3,233 (click here to show other Interactions for entry)
Diseases: Pseudomonas aeruginosa diseases
pathogen-host system
Pseudomonas aeruginosa/mammalia
P. aeruginosa strain PAK
article
Reference: Sivaneson M et al.(2011) Two-component regulatory systems in Pseudomonas aeruginosa: an intricate network mediating fimbrial and efflux pump gene expression Mol. Microbiol. 79: 1353-1366 [PMID: 21205015]

Interaction Information:

Comment It has been reported that in cystic fibrosis lungs, in which P. aeruginosa adopts the biofilm lifestyle, most isolates have an inactive MexAB-OprM pump.
Formal Description
Interaction-ID: 29828

process

P. aeruginosa infection, chronic

decreases_activity of

complex/PPI

mexAB-oprM multidrug efflux complex