General Information:

Id: 3,211 (click here to show other Interactions for entry)
Diseases: Pseudomonas aeruginosa diseases
pathogen-host system
Pseudomonas aeruginosa/mammalia
P. aeruginosa strain PAO1 and PA14
article
Reference: Mikkelsen H et al.(2009) Expression of Pseudomonas aeruginosa CupD fimbrial genes is antagonistically controlled by RcsB and the EAL-containing PvrR response regulators PLoS ONE 4: E6018 [PMID: 19547710]

Interaction Information:

Comment It was shown that, in the same way as for CupA, CupB and CupC, assembly of CupD fimbriae resulted in increased bacterial attachment to inert surfaces and biofilm formation.
Formal Description
Interaction-ID: 29645

process

CupD fimbriae assembly

increases_activity of

Comment The balance between planktonic and sessile lifestyles is known to be linked to the intracellular levels of c-di-GMP with high levels favoring biofilm formation.
Formal Description
Interaction-ID: 29660

drug/chemical compound

cdiGMP

increases_activity of

if c-di-GMP level is high