General Information:

Id: 3,151 (click here to show other Interactions for entry)
Diseases: Pseudomonas aeruginosa diseases
pathogen-host system
Pseudomonas aeruginosa/mammalia
Reference: Bardoel BW et al.(2012) Identification of an immunomodulating metalloprotease of Pseudomonas aeruginosa (IMPa) Cell. Microbiol. 14: 902-913 [PMID: 22309196]

Interaction Information:

Comment P. aeruginosa itself produces a sialidase, that is involved in respiratory infection and biofilm formation. Desialylation of mucosal surfaces increases the adherence and contributes to the colonization of P. aeruginosa. The gene encoding sialidase is among the most conserved and highest expressed in P. aeruginosa strains isolated from cystic fibrosis patients and increases biofilm formation (cited information).
Formal Description
Interaction-ID: 29015



increases_activity of