General Information:

Id: 3,140 (click here to show other Interactions for entry)
Diseases: Pseudomonas aeruginosa diseases
pathogen-host system
Pseudomonas aeruginosa/mammalia
Reference: Engel J and Eran Y(2011) Subversion of mucosal barrier polarity by pseudomonas aeruginosa. Front Microbiol 2: 114 [PMID: 21747810]

Interaction Information:

Comment P. aeruginosa binding activates a central host signaling molecule, phosphatidylinositol 3-kinase (PI3K), which is required for the synthesis of PIP3 and for activation of a downstream effector, the serine/threonine kinase Akt.
Formal Description
Interaction-ID: 30866