General Information:

Id: 3,140 (click here to show other Interactions for entry)
Diseases: Pseudomonas aeruginosa diseases
pathogen-host system
Pseudomonas aeruginosa/mammalia
Reference: Engel J and Eran Y(2011) Subversion of mucosal barrier polarity by pseudomonas aeruginosa. Front Microbiol 2: 114 [PMID: 21747810]

Interaction Information:

Comment The mucosal barrier epithelium is comprised of one or more layers of epithelial cells that have specialized and distinct apical and basolateral surfaces, separated by tight junctions (TJs), that form selective permeability barriers between biological compartments. For opportunistic pathogens, like P. aeruginosa, the mucosal barrier represents a formidable challenge to bacterial-mediated damage or entry.
Formal Description
Interaction-ID: 28915


P. aeruginosa infection

decreases_activity of

of mucosal surface