General Information:

Id: 3,113 (click here to show other Interactions for entry)
Diseases: Pseudomonas aeruginosa diseases
pathogen-host system
Pseudomonas aeruginosa/mammalia
P. aeruginosa strain PAO1
article
Reference: Soscia C et al.(2007) Cross talk between type III secretion and flagellar assembly systems in Pseudomonas aeruginosa. J. Bacteriol. 189: 3124-3132 [PMID: 17307856]

Interaction Information:

Comment The fliC mutation (nonflagellated strain) specifically influences ExoS and the T3SS. Under T3SS-inducing conditions (lacking Ca2+), ExoS secretion was significantly increased in the PAO1 delta-fliC mutant compared to that in the parental strain. The levels of elastase secretion via T2SS were similar in the PAO1 parental strain and its isogenic PAO1 delta-fliC mutant derivative.
Formal Description
Interaction-ID: 28610

cellular component

flagellum

decreases transport of

gene/protein

exoS

Comment The level of ExoS secretion was clearly enhanced in the gacA mutant strain under T3SS induction. This observation reveals that GacA negatively affects the function of T3SS, which is then controlled in a manner opposite to that for the flagellum.
Formal Description
Interaction-ID: 28619

gene/protein

gacA

decreases transport of

gene/protein

exoS