General Information:

Id: 2,932 (click here to show other Interactions for entry)
Diseases: Pseudomonas aeruginosa diseases
pathogen-host system
Pseudomonas aeruginosa/mammalia
P. aeruginosa strain PA14
article
Reference: Kesarwani M et al.(2011) A quorum sensing regulated small volatile molecule reduces acute virulence and promotes chronic infection phenotypes PLoS Pathog. 7 [PMID: 21829370]

Interaction Information:

Comment 2-amino acetophenone (2-AA) adapts P. aeruginosa for chronic infections by promoting mutations in a key acute virulence gene (lasR) and by prolonging bacterial survival.
Formal Description
Interaction-ID: 26800

drug/chemical compound

2-Amino acetophenone, 2-AA

increases_activity of

process

P. aeruginosa infection, chronic