General Information:

Id: 2,906 (click here to show other Interactions for entry)
Diseases: Pseudomonas aeruginosa diseases
pathogen-host system
Pseudomonas aeruginosa/mammalia
CF primary respiratory epithelia, infected with P. aeruginosa strain PAO1
article
Reference: Dechecchi MC et al.(2011) Modulators of sphingolipid metabolism reduce lung inflammation. Am. J. Respir. Cell Mol. Biol. 45: 825-833 [PMID: 21659660]

Interaction Information:

Comment Infection with the P. aeruginosa strain PAO1 for 4 hours up-modulated the expression of 15 (29%) genes in primary CF epithelium, with statistically validated transcription levels altered more than 2.0-fold. These genes are involved in the inflammatory response.
Formal Description
Interaction-ID: 26657

process

P. aeruginosa infection, chronic

increases_expression of

gene/protein

ICAM1

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