General Information:

Id: 2,854 (click here to show other Interactions for entry)
Diseases: Pseudomonas aeruginosa diseases
pathogen-host system
article/cited
Reference: Chand NS et al.(2011) The sensor kinase KinB regulates virulence in acute Pseudomonas aeruginosa infection. J. Bacteriol. 193: 2989-2999 [PMID: 21515773]

Interaction Information:

Comment The GacA/GacS TCS two-component signal transduction system) is thought to be a master regulator of virulence in P. aeruginosa , as it controls a number of virulence-related phenotypes, including biofilm formation and the production of several virulence factors, including pyocyanin . GacA and GacS are required for virulence in plant, nematode , insect and mouse models of acute and chronic infection. (cited information)
Formal Description
Interaction-ID: 33965

gene/protein

gacS

affects_activity of

process

P. aeruginosa infection, chronic